TY - JOUR
T1 - Infectious Mononucleosis and Acute Leukemia
AU - Rosner, Fred
AU - Grünwald, Hans W.
PY - 1981/10/16
Y1 - 1981/10/16
N2 - TO OUR knowledge, 26 cases1-15 have been reported of the association of infectious mononucleosis and acute leukemia (Table). In seven instances, the former preceded the latter by one to 36 months, in 16 cases the acute leukemia preceded the infectious mononucleosis by one to 45 months, and in three patients both diseases were diagnosed simultaneously. Twenty-one patients were children or teenagers, perhaps accounting for the 20 cases of acute lymphoblastic leukemia. Three patients had acute monocytic leukemia. The possible relationship, if any, between the Epstein-Barr (EB) virus, infectious mononucleosis, and acute leukemia is far from clear. Although the EB virus has been etiologically linked to Burkitt's lymphoma, its relation to acute lymphoblastic leukemia has not been established. It seems rather far-fetched to state that the coincidence of acute monocytic leukemia and infectious mononucleosis in two elderly patients suggests a causal relationship.15 Although one report11 suggests that the EB virus.
AB - TO OUR knowledge, 26 cases1-15 have been reported of the association of infectious mononucleosis and acute leukemia (Table). In seven instances, the former preceded the latter by one to 36 months, in 16 cases the acute leukemia preceded the infectious mononucleosis by one to 45 months, and in three patients both diseases were diagnosed simultaneously. Twenty-one patients were children or teenagers, perhaps accounting for the 20 cases of acute lymphoblastic leukemia. Three patients had acute monocytic leukemia. The possible relationship, if any, between the Epstein-Barr (EB) virus, infectious mononucleosis, and acute leukemia is far from clear. Although the EB virus has been etiologically linked to Burkitt's lymphoma, its relation to acute lymphoblastic leukemia has not been established. It seems rather far-fetched to state that the coincidence of acute monocytic leukemia and infectious mononucleosis in two elderly patients suggests a causal relationship.15 Although one report11 suggests that the EB virus.
UR - http://www.scopus.com/inward/record.url?scp=0019490081&partnerID=8YFLogxK
U2 - 10.1001/jama.1981.03320160015021
DO - 10.1001/jama.1981.03320160015021
M3 - Article
C2 - 6268857
AN - SCOPUS:0019490081
SN - 0098-7484
VL - 246
SP - 1783
EP - 1784
JO - JAMA - Journal of the American Medical Association
JF - JAMA - Journal of the American Medical Association
IS - 16
ER -