Infection rate following total joint arthroplasty in the HIV population

Brian M. Capogna; Andrew Lovy; Yossef Blum; Sun Jin Kim; Uriel R. Felsen; David S. Geller

doi:10.1016/j.arth.2012.12.021

Infection rate following total joint arthroplasty in the HIV population

Brian M. Capogna
, Andrew Lovy
, Yossef Blum
, Sun Jin Kim
, Uriel R. Felsen
, David S. Geller

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4% (3 of 69) among HIV cases compared to 0.72% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95% CI 0.64-61.0, P= 0.11). Kaplan-Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls ( P= 0.06 and P= 0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies.

Original language	English
Pages (from-to)	1254-1258
Number of pages	5
Journal	Journal of Arthroplasty
Volume	28
Issue number	8
DOIs	https://doi.org/10.1016/j.arth.2012.12.021
State	Published - Sep 2013

Keywords

Arthroplasty
Hip
Human immunodeficiency virus (HIV)
Infection
Knee

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10.1016/j.arth.2012.12.021

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title = "Infection rate following total joint arthroplasty in the HIV population",

abstract = "The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4\% (3 of 69) among HIV cases compared to 0.72\% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95\% CI 0.64-61.0, P= 0.11). Kaplan-Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls ( P= 0.06 and P= 0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies.",

keywords = "Arthroplasty, Hip, Human immunodeficiency virus (HIV), Infection, Knee",

author = "Capogna, \{Brian M.\} and Andrew Lovy and Yossef Blum and Kim, \{Sun Jin\} and Felsen, \{Uriel R.\} and Geller, \{David S.\}",

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doi = "10.1016/j.arth.2012.12.021",

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AU - Capogna, Brian M.

AU - Lovy, Andrew

AU - Blum, Yossef

AU - Kim, Sun Jin

AU - Felsen, Uriel R.

AU - Geller, David S.

PY - 2013/9

Y1 - 2013/9

N2 - The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4% (3 of 69) among HIV cases compared to 0.72% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95% CI 0.64-61.0, P= 0.11). Kaplan-Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls ( P= 0.06 and P= 0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies.

AB - The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4% (3 of 69) among HIV cases compared to 0.72% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95% CI 0.64-61.0, P= 0.11). Kaplan-Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls ( P= 0.06 and P= 0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies.

KW - Arthroplasty

KW - Hip

KW - Human immunodeficiency virus (HIV)

KW - Infection

KW - Knee

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Infection rate following total joint arthroplasty in the HIV population

Abstract

Keywords

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