Infection prophylaxis in periorbital Mohs surgery and reconstruction: a review and update to recommendations

Matthew A. DelMauro, Danielle C. Kalberer, I. Rand Rodgers

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

Mohs micrographic surgery and reconstruction is considered by many as the gold standard for treatment of cutaneous malignancies arising in the periorbital region. It has a high rate of tumor clearance and a low rate of postsurgical complications. One of the most common complications is surgical site infection. Although surgical site infection occurs in less than 3% of patients, it may result in significant morbidity. Considerable research efforts have been devoted to identifying risk factors associated with the development of a postsurgical infection. We examine the impact of endogenous factors (which determine the efficacy of a patient's immune system), exogenous factors (which influence a patient's exposure to bacterial pathogens), and antimicrobial interventions on the incidence of surgical site infection and propose evidence-based recommendations.

Original languageEnglish
Pages (from-to)323-347
Number of pages25
JournalSurvey of Ophthalmology
Volume65
Issue number3
DOIs
StatePublished - 1 May 2020
Externally publishedYes

Keywords

  • Mohs surgery
  • antibiotic prophylaxis
  • periorbital surgery
  • risk factors
  • surgical site infection

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