Infection - An underappreciated cause of bone pain in multiple myeloma

Raman Desikan, Bart Barlogie, Rajesh Sethi, Amir Toor, Dan Spoon, Edward Angtuaco, Rudy Vanhemert, Anantha VijayaGopal, Seema Singhal, Jayesh Mehta, Sundar Jagannath, Nikhil Munshi, Maurizio Zangari, Athanassios Fassas, Guido Tricot, Elias Anaissie

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Bone pain, especially back pain, is a common presenting feature of myeloma patients. We report three multiple myeloma patients with exacerbations of back pain and referred shoulder pain resulting from vertebral infections. Two patients were treated with surgery, and one patient had computerized tomography-guided percutaneous needle aspiration for diagnostic purposes. All three patients received a prolonged course of antibiotics. Vertebral infection resolved with this treatment in all three patients without any recurrence. Previous dexamethasone therapy, together with an episode of bacteraemia, appears to be a predisposing factor for vertebral infection. Magnetic resonance imaging enabled the diagnosis in all three patients.

Original languageEnglish
Pages (from-to)1047-1050
Number of pages4
JournalBritish Journal of Haematology
Issue number6
StatePublished - Mar 2003
Externally publishedYes


  • Bone pain
  • Infection
  • Myeloma


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