Infarction of intestine with massive amyloid deposition in two patients on long-term hemodialysis

Ho soon H. Choi; Debra Heller; Maria M. Picken; Gurdip S. Sidhu; Thomas Kahn

doi:10.1016/0016-5085(89)90785-3

Infarction of intestine with massive amyloid deposition in two patients on long-term hemodialysis

Ho soon H. Choi, Debra Heller, Maria M. Picken, Gurdip S. Sidhu, Thomas Kahn

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Abstract

Two patients undergoing hemodialysis for 19 and 13 yr, respectively, developed intestinal infarction with extensive amyloid deposits in the muscle layer and blood vessels. In 1 patient the deposit reacted positively with antiserum to β₂-microglobulin by immunohistochemical stain, and therefore was classified as β₂-microglobulin in origin. The amyloid protein of the other patient remains unclassified. In patients with gastrointestinal symptoms who have been undergoing hemodialysis for long periods of time, amyloidosis of the intestine should be considered.

Original language	English
Pages (from-to)	230-234
Number of pages	5
Journal	Gastroenterology
Volume	96
Issue number	1
DOIs	https://doi.org/10.1016/0016-5085(89)90785-3
State	Published - Jan 1989
Externally published	Yes

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title = "Infarction of intestine with massive amyloid deposition in two patients on long-term hemodialysis",

abstract = "Two patients undergoing hemodialysis for 19 and 13 yr, respectively, developed intestinal infarction with extensive amyloid deposits in the muscle layer and blood vessels. In 1 patient the deposit reacted positively with antiserum to β2-microglobulin by immunohistochemical stain, and therefore was classified as β2-microglobulin in origin. The amyloid protein of the other patient remains unclassified. In patients with gastrointestinal symptoms who have been undergoing hemodialysis for long periods of time, amyloidosis of the intestine should be considered.",

author = "Choi, {Ho soon H.} and Debra Heller and Picken, {Maria M.} and Sidhu, {Gurdip S.} and Thomas Kahn",

year = "1989",

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AU - Choi, Ho soon H.

AU - Heller, Debra

AU - Picken, Maria M.

AU - Sidhu, Gurdip S.

AU - Kahn, Thomas

PY - 1989/1

Y1 - 1989/1

N2 - Two patients undergoing hemodialysis for 19 and 13 yr, respectively, developed intestinal infarction with extensive amyloid deposits in the muscle layer and blood vessels. In 1 patient the deposit reacted positively with antiserum to β2-microglobulin by immunohistochemical stain, and therefore was classified as β2-microglobulin in origin. The amyloid protein of the other patient remains unclassified. In patients with gastrointestinal symptoms who have been undergoing hemodialysis for long periods of time, amyloidosis of the intestine should be considered.

AB - Two patients undergoing hemodialysis for 19 and 13 yr, respectively, developed intestinal infarction with extensive amyloid deposits in the muscle layer and blood vessels. In 1 patient the deposit reacted positively with antiserum to β2-microglobulin by immunohistochemical stain, and therefore was classified as β2-microglobulin in origin. The amyloid protein of the other patient remains unclassified. In patients with gastrointestinal symptoms who have been undergoing hemodialysis for long periods of time, amyloidosis of the intestine should be considered.

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JF - Gastroenterology

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ER -

Infarction of intestine with massive amyloid deposition in two patients on long-term hemodialysis

Abstract

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