INDUCTION OF SISTER‐CHROMATID EXCHANGES IN ICR 2A FROG CELLS EXPOSED TO 254 NM AND SOLAR UV WAVELENGTHS

Chuck C.‐K Chao, Barry S. Rosenstein

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Abstract— Exposure of ICR 2A frog cells to 254 nm UV induced the formation of sister‐chromatid exchanges (SCEs) in a fluence‐dependent manner. Cells were also exposed to the UV produced by a fluorescent sunlamp that was filtered through 8C Mylar in order to simulate the mid‐UV(290–320 nm) portion of sunlight reaching the earth's surface. In this instance, SCEs were induced in a linear fashion at low fluences but reached a plateau at a low level of induced SCEs. In addition, pretreatment of cells with the solar UV followed by exposure to 254 nm UV resulted in a significantly lower level of SCEs than in cells exposed to 254 nm UV alone.

Original languageEnglish
Pages (from-to)625-627
Number of pages3
JournalPhotochemistry and Photobiology
Volume41
Issue number5
DOIs
StatePublished - May 1985
Externally publishedYes

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