Inducing cellular aging: Enabling neurodegeneration-in-a-dish

Kristen J. Brennand

doi:10.1016/j.stem.2013.11.017

Inducing cellular aging: Enabling neurodegeneration-in-a-dish

Kristen J. Brennand

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

The immaturity of neurons differentiated from human induced pluripotent stem cells (hiPSCs) presents difficulties for modeling late-onset neurodegenerative disorders such as Parkinson's disease. Now, Miller et al. (2013) provide a strategy for inducing aging-related phenotypes in hiPSC-derived neurons, enabling in vitro study of late-onset neurodegenerative diseases.

Original language	English
Pages (from-to)	635-636
Number of pages	2
Journal	Cell Stem Cell
Volume	13
Issue number	6
DOIs	https://doi.org/10.1016/j.stem.2013.11.017
State	Published - 5 Dec 2013

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title = "Inducing cellular aging: Enabling neurodegeneration-in-a-dish",

abstract = "The immaturity of neurons differentiated from human induced pluripotent stem cells (hiPSCs) presents difficulties for modeling late-onset neurodegenerative disorders such as Parkinson's disease. Now, Miller et al. (2013) provide a strategy for inducing aging-related phenotypes in hiPSC-derived neurons, enabling in vitro study of late-onset neurodegenerative diseases.",

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AB - The immaturity of neurons differentiated from human induced pluripotent stem cells (hiPSCs) presents difficulties for modeling late-onset neurodegenerative disorders such as Parkinson's disease. Now, Miller et al. (2013) provide a strategy for inducing aging-related phenotypes in hiPSC-derived neurons, enabling in vitro study of late-onset neurodegenerative diseases.

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M3 - Short survey

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JO - Cell Stem Cell

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Inducing cellular aging: Enabling neurodegeneration-in-a-dish

Abstract

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