Independent validation of the secondary intracerebral hemorrhage score with catheter angiography and findings of emergent hematoma evacuation

Josser E.Delgado Almandoz, Bharathi D. Jagadeesan, Christopher J. Moran, Dewitte T. Cross, Gregory J. Zipfel, Jin Moo Lee, Javier M. Romero, Colin P. Derdeyn

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

BACKGROUND: The secondary intracerebral hemorrhage (SICH) score, derived from a cohort of patients with intracerebral hemorrhage examined with computed tomographic (CT) angiography, predicts a patient's risk of harboring a vascular etiology. OBJECTIVE: To validate the SICH score in an independent patient population. METHODS: We retrospectively reviewed all adults with nontraumatic ICH who presented to our institution during a 5.4-year period and were evaluated with catheter angiography or underwent emergent hematoma evacuation, and applied the SICH score to this cohort. Receiver operating characteristic analysis was performed to determine the area under the curve (AUC) and maximum operating point (MOP). Patients with subarachnoid hemorrhage in the basal cisterns were excluded. RESULTS: The study included 341 patients, with a mean age of 57.2 years (range, 18-88). Of these, 179 patients were male (52.5%) and 162 were female (47.5%). Two hundred ninety-two patients were evaluated with catheter angiography (85.6%), and 49 underwent emergent hematoma evacuation (14.4%). The SICH score successfully predicted an increasing risk of underlying vascular etiologies in the independent patient cohort, which was similar to the cohort examined with CT angiography. The MOP was reached at a SICH score >2, with the highest incidence of vascular etiologies in patients with SICH scores of 3 (18.8%), 4 (39%), and 5 (79.2%). There was no significant difference in the AUC between the 2 cohorts (0.82-0.87). CONCLUSION: The SICH score successfully predicted the risk of a patient with ICH of harboring a vascular etiology in an independent patient population. This scoring system could be used to select patients with ICH for neurovascular evaluation to exclude an underlying vascular abnormality.

Original languageEnglish
Pages (from-to)131-140
Number of pages10
JournalNeurosurgery
Volume70
Issue number1
DOIs
StatePublished - Jan 2012
Externally publishedYes

Keywords

  • Aneurysm
  • Arteriovenous malformation
  • Catheter angiography
  • Dural venous sinus thrombosis
  • Intracerebral hemorrhage

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