Increased serum N-acetyl-β-d-glucosaminidase and α-ddd-mannosidase activities in obese subjects

J. Corral, J. M. Miralles, I. J. García-Pascual, J. J. Corrales, A. Garcia-Sastre, E. Villar

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


We have studied N-acetyl-β-d-glucosaminidase and α-d-mannosidase activities in human sera from 35 control subjects, 47 normo- and hyperinsulinemic obese persons, and 12 diabetic patients after a fasting period of 12 h and at 30, 60, 90, and 120 min after an oral glucose overload. The results show a significantly higher activity of these 2 enzymes in obese subjects and diabetic patients, of similar magnitude, especially in those obese persons with a higher grade of obesity. Moreover, the activity of these glycosidases decreases in a similar way in all these 3 groups after the oral glucose overload.

Original languageEnglish
Pages (from-to)880-884
Number of pages5
JournalJournal of Molecular Medicine
Issue number10
StatePublished - Oct 1992
Externally publishedYes


  • Diabetes mellitus
  • Glycosidases
  • Obesity


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