Increased erythrocyte sodium permeability in patients with Bartter's syndrome

J. F. Oliver, V. B. Delaney, E. Bourke

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Erythrocyte sodium kinetics were studied in 5 siblings with Bartter's syndrome (BS) and their relatives. The relatives were similar to controls in all parameters of sodium transport. Patients with BS had an elevated red cell sodium concentration. 'Passive', ouabain uninhibitible, sodium efflux rate constant was significantly increased and there was also a significant increase in sodium influx. These findings indicate increased erythrocyte sodium permeability in BS.

Original languageEnglish
Pages (from-to)225-230
Number of pages6
JournalMineral and Electrolyte Metabolism
Volume1
Issue number4
StatePublished - 1978
Externally publishedYes

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