Erythrocyte sodium kinetics were studied in 5 siblings with Bartter's syndrome (BS) and their relatives. The relatives were similar to controls in all parameters of sodium transport. Patients with BS had an elevated red cell sodium concentration. 'Passive', ouabain uninhibitible, sodium efflux rate constant was significantly increased and there was also a significant increase in sodium influx. These findings indicate increased erythrocyte sodium permeability in BS.
|Number of pages
|Mineral and Electrolyte Metabolism
|Published - 1978