TY - JOUR
T1 - Increased Elevation of Peripheral Leukocyte Counts by Infusion of Histocompatible Granulocytes
AU - Higby, D. J.
AU - Mishler, John Milton
AU - Cohen, E.
AU - Rhomberg, W.
AU - Nicora, R. W.
AU - Holland, J. F.
PY - 1974/8
Y1 - 1974/8
N2 - Abstract. The results of 38 HL‐A and other antigen matching studies revealed an inverse relationship between the percent of donor‐recipient serologic discordance and increases in recipient granulocyte levels 1 h after infusion of donor cells. Selected unrelated, parent, and sibling donors possessing mean percent serologic discordances of 33, 22, and 16, respectively, increased postinfusion granulocyte counts by 10, 46, and 117%, respectively. A mean of 1.58 × 1010 total granulocytes collected from sibling donors was associated with a significant elevation of recipient levels, as compared to unfavorable results with the infusion of 2.05 × 1010 and 2.31 × 1010 total granulocytes harvested from less compatible parent and selected unrelated donors, respectively.
AB - Abstract. The results of 38 HL‐A and other antigen matching studies revealed an inverse relationship between the percent of donor‐recipient serologic discordance and increases in recipient granulocyte levels 1 h after infusion of donor cells. Selected unrelated, parent, and sibling donors possessing mean percent serologic discordances of 33, 22, and 16, respectively, increased postinfusion granulocyte counts by 10, 46, and 117%, respectively. A mean of 1.58 × 1010 total granulocytes collected from sibling donors was associated with a significant elevation of recipient levels, as compared to unfavorable results with the infusion of 2.05 × 1010 and 2.31 × 1010 total granulocytes harvested from less compatible parent and selected unrelated donors, respectively.
UR - http://www.scopus.com/inward/record.url?scp=0016152077&partnerID=8YFLogxK
U2 - 10.1111/j.1423-0410.1974.tb02406.x
DO - 10.1111/j.1423-0410.1974.tb02406.x
M3 - Article
C2 - 4212083
AN - SCOPUS:0016152077
SN - 0042-9007
VL - 27
SP - 186
EP - 189
JO - Vox Sanguinis
JF - Vox Sanguinis
IS - 2
ER -