Incident alopecia areata and vitiligo in adult women with atopic dermatitis: Nurses’ Health Study 2

A. M. Drucker; J. M. Thompson; W. Q. Li; E. Cho; T. Li; E. Guttman-Yassky; A. A. Qureshi

doi:10.1111/all.13128

Incident alopecia areata and vitiligo in adult women with atopic dermatitis: Nurses’ Health Study 2

A. M. Drucker, J. M. Thompson, W. Q. Li, E. Cho, T. Li, E. Guttman-Yassky, A. A. Qureshi

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

We aimed to determine the risk of alopecia areata (AA) and vitiligo associated with atopic dermatitis (AD) in a large cohort of US women, the Nurses’ Health Study 2. We used logistic regression to calculate age- and multivariate-adjusted odds ratios to determine the risk of incident AA and vitiligo associated with AD diagnosed in or before 2009. A total of 87 406 and 87 447 participants were included in the AA and vitiligo analyses, respectively. A history of AD in 2009 was reported in 11% of participants. There were 147 incident cases of AA and 98 incident cases of vitiligo over 2 years of follow-up. AD was associated with increased risk of developing AA (OR 1.80, 95% CI 1.18–2.76) and vitiligo (OR 2.14, 95% CI 1.29–3.54) in multivariate models. In this study of US women, AD was associated with increased risk of incident vitiligo and AA in adulthood.

Original language	English
Pages (from-to)	831-834
Number of pages	4
Journal	Allergy: European Journal of Allergy and Clinical Immunology
Volume	72
Issue number	5
DOIs	https://doi.org/10.1111/all.13128
State	Published - 1 May 2017

Keywords

alopecia areata
atopic dermatitis
comorbidities
epidemiology
vitiligo

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title = "Incident alopecia areata and vitiligo in adult women with atopic dermatitis: Nurses{\textquoteright} Health Study 2",

abstract = "We aimed to determine the risk of alopecia areata (AA) and vitiligo associated with atopic dermatitis (AD) in a large cohort of US women, the Nurses{\textquoteright} Health Study 2. We used logistic regression to calculate age- and multivariate-adjusted odds ratios to determine the risk of incident AA and vitiligo associated with AD diagnosed in or before 2009. A total of 87 406 and 87 447 participants were included in the AA and vitiligo analyses, respectively. A history of AD in 2009 was reported in 11% of participants. There were 147 incident cases of AA and 98 incident cases of vitiligo over 2 years of follow-up. AD was associated with increased risk of developing AA (OR 1.80, 95% CI 1.18–2.76) and vitiligo (OR 2.14, 95% CI 1.29–3.54) in multivariate models. In this study of US women, AD was associated with increased risk of incident vitiligo and AA in adulthood.",

keywords = "alopecia areata, atopic dermatitis, comorbidities, epidemiology, vitiligo",

author = "Drucker, {A. M.} and Thompson, {J. M.} and Li, {W. Q.} and E. Cho and T. Li and E. Guttman-Yassky and Qureshi, {A. A.}",

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AU - Drucker, A. M.

AU - Thompson, J. M.

AU - Li, W. Q.

AU - Cho, E.

AU - Li, T.

AU - Guttman-Yassky, E.

AU - Qureshi, A. A.

PY - 2017/5/1

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N2 - We aimed to determine the risk of alopecia areata (AA) and vitiligo associated with atopic dermatitis (AD) in a large cohort of US women, the Nurses’ Health Study 2. We used logistic regression to calculate age- and multivariate-adjusted odds ratios to determine the risk of incident AA and vitiligo associated with AD diagnosed in or before 2009. A total of 87 406 and 87 447 participants were included in the AA and vitiligo analyses, respectively. A history of AD in 2009 was reported in 11% of participants. There were 147 incident cases of AA and 98 incident cases of vitiligo over 2 years of follow-up. AD was associated with increased risk of developing AA (OR 1.80, 95% CI 1.18–2.76) and vitiligo (OR 2.14, 95% CI 1.29–3.54) in multivariate models. In this study of US women, AD was associated with increased risk of incident vitiligo and AA in adulthood.

AB - We aimed to determine the risk of alopecia areata (AA) and vitiligo associated with atopic dermatitis (AD) in a large cohort of US women, the Nurses’ Health Study 2. We used logistic regression to calculate age- and multivariate-adjusted odds ratios to determine the risk of incident AA and vitiligo associated with AD diagnosed in or before 2009. A total of 87 406 and 87 447 participants were included in the AA and vitiligo analyses, respectively. A history of AD in 2009 was reported in 11% of participants. There were 147 incident cases of AA and 98 incident cases of vitiligo over 2 years of follow-up. AD was associated with increased risk of developing AA (OR 1.80, 95% CI 1.18–2.76) and vitiligo (OR 2.14, 95% CI 1.29–3.54) in multivariate models. In this study of US women, AD was associated with increased risk of incident vitiligo and AA in adulthood.

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KW - vitiligo

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Incident alopecia areata and vitiligo in adult women with atopic dermatitis: Nurses’ Health Study 2

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