In vivo X-ray fluorescence of lead in bone using K X-ray excitation with 109Cd sources: Radiation dosimetry studies

Andrew C. Todd; Fiona E. McNeill; Jeffrey E. Palethorpe; Denise E. Peach; David R. Chettle; Michael J. Tobin; Sandra J. Strosko; Jerry C. Rosen

doi:10.1016/S0013-9351(05)80073-8

In vivo X-ray fluorescence of lead in bone using K X-ray excitation with ¹⁰⁹Cd sources: Radiation dosimetry studies

Andrew C. Todd
, Fiona E. McNeill
, Jeffrey E. Palethorpe
, Denise E. Peach
, David R. Chettle
, Michael J. Tobin
, Sandra J. Strosko
, Jerry C. Rosen

Research output: Contribution to journal › Article › peer-review

74 Scopus citations

Abstract

Independent experiments have been performed at two centers, to evaluate the dosimetric properties of their respective ¹⁰⁹Cd K X-ray fluorescence (XRF) bone lead measurement systems. Measurements were made of the dose to several points on the skin of the lower leg, at the surface of the tibia, in the red marrow tibia cavity, at the midcalf, and in the abdominal region occupied by the conceptus. Overall agreement between the two data sets was found. Similarities and differences are discussed. The effective dose values for an in vivo measurement of tibia lead concentration in 1-, 5-, and 10-year-old and adult subjects were calculated from one data set to be 1100, 420, 190, and 34/38 (male/female) nSv, respectively, for an in vivo median precision (one standard deviation) of 4.9 μg Pb (g bone mineral)^-1 for a 30-min adult measurement.

Original language	English
Pages (from-to)	117-132
Number of pages	16
Journal	Environmental Research
Volume	57
Issue number	2
DOIs	https://doi.org/10.1016/S0013-9351(05)80073-8
State	Published - Apr 1992
Externally published	Yes

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@article{3dc8ddc7631b4981a00457dd0446e389,

title = "In vivo X-ray fluorescence of lead in bone using K X-ray excitation with 109Cd sources: Radiation dosimetry studies",

abstract = "Independent experiments have been performed at two centers, to evaluate the dosimetric properties of their respective 109Cd K X-ray fluorescence (XRF) bone lead measurement systems. Measurements were made of the dose to several points on the skin of the lower leg, at the surface of the tibia, in the red marrow tibia cavity, at the midcalf, and in the abdominal region occupied by the conceptus. Overall agreement between the two data sets was found. Similarities and differences are discussed. The effective dose values for an in vivo measurement of tibia lead concentration in 1-, 5-, and 10-year-old and adult subjects were calculated from one data set to be 1100, 420, 190, and 34/38 (male/female) nSv, respectively, for an in vivo median precision (one standard deviation) of 4.9 μg Pb (g bone mineral)-1 for a 30-min adult measurement.",

author = "Todd, \{Andrew C.\} and McNeill, \{Fiona E.\} and Palethorpe, \{Jeffrey E.\} and Peach, \{Denise E.\} and Chettle, \{David R.\} and Tobin, \{Michael J.\} and Strosko, \{Sandra J.\} and Rosen, \{Jerry C.\}",

year = "1992",

month = apr,

doi = "10.1016/S0013-9351(05)80073-8",

language = "English",

volume = "57",

pages = "117--132",

journal = "Environmental Research",

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publisher = "Academic Press Inc.",

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}

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T1 - In vivo X-ray fluorescence of lead in bone using K X-ray excitation with 109Cd sources

T2 - Radiation dosimetry studies

AU - Todd, Andrew C.

AU - McNeill, Fiona E.

AU - Palethorpe, Jeffrey E.

AU - Peach, Denise E.

AU - Chettle, David R.

AU - Tobin, Michael J.

AU - Strosko, Sandra J.

AU - Rosen, Jerry C.

PY - 1992/4

Y1 - 1992/4

N2 - Independent experiments have been performed at two centers, to evaluate the dosimetric properties of their respective 109Cd K X-ray fluorescence (XRF) bone lead measurement systems. Measurements were made of the dose to several points on the skin of the lower leg, at the surface of the tibia, in the red marrow tibia cavity, at the midcalf, and in the abdominal region occupied by the conceptus. Overall agreement between the two data sets was found. Similarities and differences are discussed. The effective dose values for an in vivo measurement of tibia lead concentration in 1-, 5-, and 10-year-old and adult subjects were calculated from one data set to be 1100, 420, 190, and 34/38 (male/female) nSv, respectively, for an in vivo median precision (one standard deviation) of 4.9 μg Pb (g bone mineral)-1 for a 30-min adult measurement.

AB - Independent experiments have been performed at two centers, to evaluate the dosimetric properties of their respective 109Cd K X-ray fluorescence (XRF) bone lead measurement systems. Measurements were made of the dose to several points on the skin of the lower leg, at the surface of the tibia, in the red marrow tibia cavity, at the midcalf, and in the abdominal region occupied by the conceptus. Overall agreement between the two data sets was found. Similarities and differences are discussed. The effective dose values for an in vivo measurement of tibia lead concentration in 1-, 5-, and 10-year-old and adult subjects were calculated from one data set to be 1100, 420, 190, and 34/38 (male/female) nSv, respectively, for an in vivo median precision (one standard deviation) of 4.9 μg Pb (g bone mineral)-1 for a 30-min adult measurement.

UR - https://www.scopus.com/pages/publications/0026554931

U2 - 10.1016/S0013-9351(05)80073-8

DO - 10.1016/S0013-9351(05)80073-8

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JO - Environmental Research

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ER -

In vivo X-ray fluorescence of lead in bone using K X-ray excitation with 109Cd sources: Radiation dosimetry studies

Abstract

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In vivo X-ray fluorescence of lead in bone using K X-ray excitation with ¹⁰⁹Cd sources: Radiation dosimetry studies