In vivo agents and markers for endomicroscopy

Daniel P. Perl, Sharmila Anandasabapathy

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

Novel in vivo agents and molecular markers are steadily enhancing the field of endoscopy. By resolving glandular patterns and subcellular features, these targeted agents can provide endoscopists with near histologic-grade images of gastrointestinal disease. This chapter will review the clinical research in vital-dye, contrast, peptide, molecular, and mucolytic agents that have been studied to better target suspicious lesions for biopsy. To start off, the characteristics of each agent will be summarized. Then, the chapter will examine each organ system (esophagus, stomach, and colon) in turn and discuss how agents and their respective imaging systems have performed.

Original languageEnglish
Title of host publicationEndoscopic Imaging Techniques and Tools
PublisherSpringer International Publishing
Pages147-173
Number of pages27
ISBN (Electronic)9783319300535
ISBN (Print)9783319300511
DOIs
StatePublished - 1 Jan 2016
Externally publishedYes

Keywords

  • Chromoendoscopy
  • Confocal laser endomicroscopy
  • Endocytoscopy
  • High-resolution endomicroscopy
  • Multispectral digital microscopy
  • Near-infrared imaging
  • Optical molecular imaging

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