TY - JOUR
T1 - In Vitro Analysis of Cell Salvage Blood Collection With a Laparoscopic Suction Device
AU - Nagarsheth, Nimesh P.
AU - Fenske, Suzanne Silverman
AU - Shah, Apurva
AU - Moshier, Erin
AU - Stahl, Rosalyn
AU - Shander, Aryeh
PY - 2013/1
Y1 - 2013/1
N2 - Study Objective: To determine whether cell salvage blood collection with a laparoscopic suction device is inferior to use of a traditional Yankauer suction device. Design: Prospective, in vitro study. Setting: Academic teaching hospital. Interventions: Individual units of donated packed red blood cells were diluted with normal saline solution to a hematocrit level of 21%. The blood was divided into 2 equal parts and then suctioned with either a laparoscopic suction device or a Yankauer plastic suction catheter tip connected to double-lumen cell salvage tubing with a diluted heparin drip and a vacuum pressure of 100 mm Hg. Collected blood was processed with a cell salvage device. Red blood cell volume was calculated by multiplying the hematocrit level by the total volume of blood product at the time of testing. Mean hemolysis indexes were compared between the laparoscopic and Yankauer method of blood collection by use of a 2-sample t test. Assuming a clinically acceptable limit of loss to be 7%, percent loss in red blood cell volume was tested with a 95% one-sided confidence limit to assess noninferiority. Measurements and Results: The mean hemolysis index was 43.33 with laparoscopic suction method and 34.67 with the Yankauer suction method. The mean difference was 8.67 and was not considered significant (p = .074). The percent loss in red blood cell volume after collection and cell salvage processing was 33.2% with the laparoscopic suction method and 29.57% with the Yankauer method. The mean difference was 3.63% and was within the acceptable 7% loss limit for noninferiority (p = .0278). Conclusions: Laparoscopic blood collection is not inferior to the standard Yankauer method for cell salvage collection.
AB - Study Objective: To determine whether cell salvage blood collection with a laparoscopic suction device is inferior to use of a traditional Yankauer suction device. Design: Prospective, in vitro study. Setting: Academic teaching hospital. Interventions: Individual units of donated packed red blood cells were diluted with normal saline solution to a hematocrit level of 21%. The blood was divided into 2 equal parts and then suctioned with either a laparoscopic suction device or a Yankauer plastic suction catheter tip connected to double-lumen cell salvage tubing with a diluted heparin drip and a vacuum pressure of 100 mm Hg. Collected blood was processed with a cell salvage device. Red blood cell volume was calculated by multiplying the hematocrit level by the total volume of blood product at the time of testing. Mean hemolysis indexes were compared between the laparoscopic and Yankauer method of blood collection by use of a 2-sample t test. Assuming a clinically acceptable limit of loss to be 7%, percent loss in red blood cell volume was tested with a 95% one-sided confidence limit to assess noninferiority. Measurements and Results: The mean hemolysis index was 43.33 with laparoscopic suction method and 34.67 with the Yankauer suction method. The mean difference was 8.67 and was not considered significant (p = .074). The percent loss in red blood cell volume after collection and cell salvage processing was 33.2% with the laparoscopic suction method and 29.57% with the Yankauer method. The mean difference was 3.63% and was within the acceptable 7% loss limit for noninferiority (p = .0278). Conclusions: Laparoscopic blood collection is not inferior to the standard Yankauer method for cell salvage collection.
KW - Bloodless surgery
KW - Cell salvage
KW - Cell saver
KW - Intraoperative autologous blood transfusion
KW - Laparoscopic cell salvage
KW - Laparoscopic suction device
UR - http://www.scopus.com/inward/record.url?scp=84872320677&partnerID=8YFLogxK
U2 - 10.1016/j.jmig.2012.10.002
DO - 10.1016/j.jmig.2012.10.002
M3 - Article
C2 - 23312250
AN - SCOPUS:84872320677
VL - 20
SP - 104
EP - 106
JO - Journal of Minimally Invasive Gynecology
JF - Journal of Minimally Invasive Gynecology
SN - 1553-4650
IS - 1
ER -