In situ hybridization reveals VIP precursor mRNA-containing neurons in monkey and rat neocortex

Deanna L. Benson; Paul J. Isackson; Edward G. Jones

doi:10.1016/0169-328X(91)90145-N

In situ hybridization reveals VIP precursor mRNA-containing neurons in monkey and rat neocortex

Deanna L. Benson, Paul J. Isackson, Edward G. Jones

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

The cDNAs encoding monkey vasoactive intestinal polypeptide (VIP) and PHM-27 and rat VIP and PHI-27 were cloned and used to generate antisense RNA probes. Using in situ hybridization, neurons expressing the VIP/PHM or VIP/PHI precursor mRNAs were localized in monkey and rat somatic sensory and visual cortex. In both neocortical areas of both species, labeled cells were observed in all 6 layers as well as the subcortical white matter.

Original language	English
Pages (from-to)	169-174
Number of pages	6
Journal	Molecular Brain Research
Volume	9
Issue number	1-2
DOIs	https://doi.org/10.1016/0169-328X(91)90145-N
State	Published - Jan 1991
Externally published	Yes

Keywords

PHI-27
PHM-27
Somatic sensory cortex
Vasoactive intestinal polypeptide
Visual cortex

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10.1016/0169-328X(91)90145-N

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title = "In situ hybridization reveals VIP precursor mRNA-containing neurons in monkey and rat neocortex",

abstract = "The cDNAs encoding monkey vasoactive intestinal polypeptide (VIP) and PHM-27 and rat VIP and PHI-27 were cloned and used to generate antisense RNA probes. Using in situ hybridization, neurons expressing the VIP/PHM or VIP/PHI precursor mRNAs were localized in monkey and rat somatic sensory and visual cortex. In both neocortical areas of both species, labeled cells were observed in all 6 layers as well as the subcortical white matter.",

keywords = "PHI-27, PHM-27, Somatic sensory cortex, Vasoactive intestinal polypeptide, Visual cortex",

author = "Benson, {Deanna L.} and Isackson, {Paul J.} and Jones, {Edward G.}",

year = "1991",

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doi = "10.1016/0169-328X(91)90145-N",

language = "English",

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pages = "169--174",

journal = "Molecular Brain Research",

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AU - Benson, Deanna L.

AU - Isackson, Paul J.

AU - Jones, Edward G.

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Y1 - 1991/1

N2 - The cDNAs encoding monkey vasoactive intestinal polypeptide (VIP) and PHM-27 and rat VIP and PHI-27 were cloned and used to generate antisense RNA probes. Using in situ hybridization, neurons expressing the VIP/PHM or VIP/PHI precursor mRNAs were localized in monkey and rat somatic sensory and visual cortex. In both neocortical areas of both species, labeled cells were observed in all 6 layers as well as the subcortical white matter.

AB - The cDNAs encoding monkey vasoactive intestinal polypeptide (VIP) and PHM-27 and rat VIP and PHI-27 were cloned and used to generate antisense RNA probes. Using in situ hybridization, neurons expressing the VIP/PHM or VIP/PHI precursor mRNAs were localized in monkey and rat somatic sensory and visual cortex. In both neocortical areas of both species, labeled cells were observed in all 6 layers as well as the subcortical white matter.

KW - PHI-27

KW - PHM-27

KW - Somatic sensory cortex

KW - Vasoactive intestinal polypeptide

KW - Visual cortex

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U2 - 10.1016/0169-328X(91)90145-N

DO - 10.1016/0169-328X(91)90145-N

M3 - Article

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SP - 169

EP - 174

JO - Molecular Brain Research

JF - Molecular Brain Research

IS - 1-2

ER -

In situ hybridization reveals VIP precursor mRNA-containing neurons in monkey and rat neocortex

Abstract

Keywords

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