@article{e06a8425b07a40878b021b6a10756aba,
title = "Improving adherence in mental health service users with severe mental illness in South Africa: A pilot randomized controlled trial of a treatment partner and text message intervention vs. treatment as usual PACTR201610001830190 PACTR",
abstract = "Objectives: Medication non-adherence is a significant problem in treatment of severe mental disorders and is associated with poor clinical outcomes and increased demand on services. Task-shifting interventions incorporating mobile health may improve adherence in mental health service users in low- and middle-income countries. Seventy-seven participants were recruited from a psychiatric hospital in Cape Town, with 42 randomized to receive the intervention and 35 to treatment as usual. Intervention pairs underwent treatment-partner contracting and psychoeducation, and received monthly text message reminders of clinic appointments. Primary outcomes were intervention acceptability and feasibility. Secondary outcome for efficacy were adherence to clinic visit; relapse; quality of life; symptomatic relief and medication adherence. Results: Treatment partner and psychoeducation components were acceptable and feasible. The text message component was acceptable but not feasible in its current form. Efficacy outcomes favoured the intervention but did not reach statistical significance. A treatment-partner intervention is acceptable and feasible in a low- and middle-income setting. Work is needed to ensure that additional components of such interventions are tailored to the local context. Appropriately powered efficacy studies are needed.",
keywords = "Adherence, Mental health, Mobile health, Task-shifting, Text message, Treatment partner",
author = "Goodman Sibeko and Henk Temmingh and Sumaya Mall and Peter Williams-Ashman and Graham Thornicroft and Susser, {Ezra S.} and Crick Lund and Stein, {Dan J.} and Milligan, {Peter D.}",
note = "Funding Information: Initial funding for this study was received from the World Psychiatric Associa‑ tion. DS AND GS were supported by the South African Medical Research Council Unit on Anxiety and Stress Disorders. CL was supported by the Programme for Improving Mental health care (PRIME), funded by UK aid from the UK Government, however the views expressed do not necessarily reflect the UK Government{\textquoteright}s official policies. SM has received support from a National Research Foundation, South Africa postdoctoral fellowship as well as a Harry Crossley Foundation post‑doctoral fellowship. PW, HT and PM are specialist psychiatrists in public service with no external funding. GT is supported by the National Institute for Health Research (NIHR) Collaboration for Leader‑ ship in Applied Health Research and Care South London at King{\textquoteright}s College London Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. GT acknowledges financial support from the Department of Health via the National Institute for Health Research (NIHR) Biomedical Research Centre and Dementia Unit awarded to South London and Maudsley NHS Foundation Trust in partnership with King{\textquoteright}s College London and King{\textquoteright}s College Hospital NHS Foundation Trust. GT is supported by the European Union Seventh Framework Programme (FP7/2007‑2013) Emerald project. ES{\textquoteright}s in‑kind contribution was supported by New York State Psychiatric Institute, New York. Publisher Copyright: {\textcopyright} 2017 The Author(s).",
year = "2017",
month = nov,
day = "9",
doi = "10.1186/s13104-017-2915-z",
language = "English",
volume = "10",
journal = "BMC Research Notes",
issn = "1756-0500",
publisher = "BioMed Central Ltd.",
number = "1",
}