@article{81931680069c4b77a890d8fc6a494068,
title = "Importance of birth weight as a risk factor for severe retinopathy of prematurity when gestational age is 30 or more weeks",
abstract = "• Purpose: To determine whether birth weight less than 1500 g is a relevant guideline indicating the need for examination for retinopathy of prematurity (ROP) when gestational age at birth is 30 or more completed weeks. • Design: A retrospective observational cohort study. • Methods: A total of 266 infants in a single institutional neonatal intensive care unit (NICU), whose gestational age at birth was 30 or more weeks but whose birth weight was less than 1500 g, were examined according to published guidelines. Infants with lethal congenital anomalies or major ocular abnormalities were excluded. Outcomes were vascularization in retinal zone III without a prior need for treatment, or ROP warranting treatment. • Results: A study outcome was reached by 212 infants. Two hundred and eleven (99.5%) became vascularized through zone III without needing treatment. Only 1 (0.5%) required treatment for ROP. The 95% confidence interval for the occurrence rate of ROP requiring treatment in this cohort was 0.01%-2.60%. • Conclusion: Our results suggest that the occurrence rates of ROP requiring treatment in infants with gestational age 30 or more weeks and birth weight less than 1500 g is very low, and could indicate the need to revise examination guidelines for this subgroup of infants.",
author = "Pierce, {Leslie M.} and Raab, {Edward L.} and Holzman, {Ian R.} and Ginsburg, {Robin N.} and Brodie, {Scott E.} and Annemarie Stroustrup",
note = "Funding Information: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Drs Raab and Holzman receive payment for serving as medical expert witnesses for several law firms. Dr Holzman receives support from an institutional grant from AHRQ for a federal quality measure program. Dr Stroustrup receives support from National Institutes of Health institutional grants KL2 RR029885 and K23 ES022268 . This study was supported in part by an unrestricted grant from Research to Prevent Blindness , Inc, New York, New York (Drs Raab, Ginsburg, and Brodie). Dr Pierce was supported by a travel grant from the Eastern Society of Pediatric Research . Contributions of authors: design of the study (L.M.P., E.L.R., I.R.H., A.S.); conduct of the study (L.M.P., E.L.R., R.N.G., S.E.B., A.S.); data collection (L.M.P., E.L.R., R.N.G., A.S.); management (E.L.R., A.S.); analysis and interpretation (L.M.P., E.L.R., S.E.B., A.S.); principal writer (E.L.R.); review/approval of manuscript (L.M.P., E.L.R., I.R.H., R.N.G., S.E.B., A.S.). ",
year = "2014",
month = jun,
doi = "10.1016/j.ajo.2014.02.045",
language = "English",
volume = "157",
pages = "1227--1230.e2",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "6",
}