Abstract
Implementation of pharmacogenetic-guided warfarin dosing has been hindered by inconsistent results from reported clinical trials and a lack of available algorithms that include alleles prevalent in non-white populations. However, current evidence indicates that algorithm-guided dosing is more accurate than empirical dosing. To facilitate multiethnic algorithm-guided warfarin dosing using preemptive genetic testing, we developed a strategy that accounts for the complexity of race and leverages electronic health records for algorithm variables and deploying point-of-care dose recommendations.
Original language | English |
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Pages (from-to) | 427-430 |
Number of pages | 4 |
Journal | Clinical Pharmacology and Therapeutics |
DOIs | |
State | Published - 1 Nov 2016 |