Impairment of Myocardial Glutamine Homeostasis Induced by Suppression of the Amino Acid Carrier SLC1A5 in Failing Myocardium

Peter J. Kennel; Xianghai Liao; Amit Saha; Ruiping Ji; Xiaokan Zhang; Estibaliz Castillero; Danielle Brunjes; Hiroo Takayama; Yoshifumi Naka; Tiffany Thomas; Isaac George; Donna Mancini; P. Christian Schulze

doi:10.1161/CIRCHEARTFAILURE.119.006336

Impairment of Myocardial Glutamine Homeostasis Induced by Suppression of the Amino Acid Carrier SLC1A5 in Failing Myocardium

Peter J. Kennel
, Xianghai Liao
, Amit Saha
, Ruiping Ji
, Xiaokan Zhang
, Estibaliz Castillero
, Danielle Brunjes
, Hiroo Takayama
, Yoshifumi Naka
, Tiffany Thomas
, Isaac George
, Donna Mancini
, P. Christian Schulze

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Original language	English
Article number	e006336
Journal	Circulation: Heart Failure
Volume	12
Issue number	12
DOIs	https://doi.org/10.1161/CIRCHEARTFAILURE.119.006336
State	Published - 1 Dec 2019
Externally published	Yes

Keywords

glutamine
heart failure
homeostasis
myocardium
phenotype

Access to Document

10.1161/CIRCHEARTFAILURE.119.006336

Cite this

Kennel, P. J., Liao, X., Saha, A., Ji, R., Zhang, X., Castillero, E., Brunjes, D., Takayama, H., Naka, Y., Thomas, T., George, I., Mancini, D., & Christian Schulze, P. (2019). Impairment of Myocardial Glutamine Homeostasis Induced by Suppression of the Amino Acid Carrier SLC1A5 in Failing Myocardium. Circulation: Heart Failure, 12(12), Article e006336. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006336

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keywords = "glutamine, heart failure, homeostasis, myocardium, phenotype",

author = "Kennel, \{Peter J.\} and Xianghai Liao and Amit Saha and Ruiping Ji and Xiaokan Zhang and Estibaliz Castillero and Danielle Brunjes and Hiroo Takayama and Yoshifumi Naka and Tiffany Thomas and Isaac George and Donna Mancini and \{Christian Schulze\}, P.",

note = "Funding Information: This study was supported by grants from the National Institutes of Health to Dr Schulze (RO1 HL114813).",

year = "2019",

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doi = "10.1161/CIRCHEARTFAILURE.119.006336",

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Kennel, PJ, Liao, X, Saha, A, Ji, R, Zhang, X, Castillero, E, Brunjes, D, Takayama, H, Naka, Y, Thomas, T, George, I, Mancini, D & Christian Schulze, P 2019, 'Impairment of Myocardial Glutamine Homeostasis Induced by Suppression of the Amino Acid Carrier SLC1A5 in Failing Myocardium', Circulation: Heart Failure, vol. 12, no. 12, e006336. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006336

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T1 - Impairment of Myocardial Glutamine Homeostasis Induced by Suppression of the Amino Acid Carrier SLC1A5 in Failing Myocardium

AU - Kennel, Peter J.

AU - Liao, Xianghai

AU - Saha, Amit

AU - Ji, Ruiping

AU - Zhang, Xiaokan

AU - Castillero, Estibaliz

AU - Brunjes, Danielle

AU - Takayama, Hiroo

AU - Naka, Yoshifumi

AU - Thomas, Tiffany

AU - George, Isaac

AU - Mancini, Donna

AU - Christian Schulze, P.

N1 - Funding Information: This study was supported by grants from the National Institutes of Health to Dr Schulze (RO1 HL114813).

PY - 2019/12/1

Y1 - 2019/12/1

KW - glutamine

KW - heart failure

KW - homeostasis

KW - myocardium

KW - phenotype

UR - https://www.scopus.com/pages/publications/85076482942

U2 - 10.1161/CIRCHEARTFAILURE.119.006336

DO - 10.1161/CIRCHEARTFAILURE.119.006336

M3 - Article

C2 - 31826641

AN - SCOPUS:85076482942

SN - 1941-3289

VL - 12

JO - Circulation: Heart Failure

JF - Circulation: Heart Failure

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