TY - JOUR
T1 - Impact of Left Ventricular Outflow Tract Obstruction on Coronary Physiological Assessment
AU - Harano, Yoshihiro
AU - Kawase, Yoshiaki
AU - Warisawa, Takayuki
AU - Matsuo, Hitoshi
N1 - Publisher Copyright:
© 2023
PY - 2023/8
Y1 - 2023/8
N2 - Hypertrophic cardiomyopathy which is known to occasionally have coronary artery disease as concomitant disease may require coronary physiological assessment (Okayama et al., 2015; Shin et al., 2019 [1,2]). However, no study clarified the impact of left ventricular outflow tract obstruction on coronary physiological assessment. Herein, a case of hypertrophic obstructive cardiomyopathy concomitant with moderate coronary lesion was reported, in which dynamic change of physiological values was observed during pharmacological intervention. Specifically, fractional flow reserve (FFR) and resting full-cycle ratio (RFR) changed in an opposite fashion when the left ventricular outflow tract pressure gradient was decreased by intravenous propranolol and cibenzoline: in FFR from 0.83 to 0.79 and in RFR from 0.73 to 0.91. Cardiologists should pay attention to the presence of concomitant cardiovascular disorders in interpreting coronary physiological data.
AB - Hypertrophic cardiomyopathy which is known to occasionally have coronary artery disease as concomitant disease may require coronary physiological assessment (Okayama et al., 2015; Shin et al., 2019 [1,2]). However, no study clarified the impact of left ventricular outflow tract obstruction on coronary physiological assessment. Herein, a case of hypertrophic obstructive cardiomyopathy concomitant with moderate coronary lesion was reported, in which dynamic change of physiological values was observed during pharmacological intervention. Specifically, fractional flow reserve (FFR) and resting full-cycle ratio (RFR) changed in an opposite fashion when the left ventricular outflow tract pressure gradient was decreased by intravenous propranolol and cibenzoline: in FFR from 0.83 to 0.79 and in RFR from 0.73 to 0.91. Cardiologists should pay attention to the presence of concomitant cardiovascular disorders in interpreting coronary physiological data.
KW - Case report
KW - Coronary artery disease
KW - Coronary physiology
KW - Fractional flow reserve
KW - Left ventricular outflow tract obstruction
KW - Resting full-cycle ratio
UR - http://www.scopus.com/inward/record.url?scp=85149634791&partnerID=8YFLogxK
U2 - 10.1016/j.carrev.2023.01.018
DO - 10.1016/j.carrev.2023.01.018
M3 - Article
C2 - 36863975
AN - SCOPUS:85149634791
SN - 1553-8389
VL - 53
SP - S317-S319
JO - Cardiovascular Revascularization Medicine
JF - Cardiovascular Revascularization Medicine
ER -