Immunoreactive epidermal growth factor in human amniotic fluid

T. Barka, H. Van Der Noen, E. W. Gresik, T. Kerenyi

Research output: Contribution to journalArticlepeer-review

70 Scopus citations

Abstract

Human amniotic fluids, obtained by amniocentesis at 16-24 weeks of gestation, were analyzed for epidermal growth factor (EGF) by using a heterologous radioimmunoassay. The range of EGF in 28 amniotic fluids was 0.06-1 ng/ml. Much higher levels of EGF up to 26 ng/ml, were detected in 3 amniotic fluids. Competitive binding assays and chromatography of concentrated amniotic fluids provided additional evidence for the presence of immunoreactive EGF in amniotic fluid.

Original languageEnglish
Pages (from-to)679-684
Number of pages6
JournalMount Sinai Journal of Medicine
Volume45
Issue number6
StatePublished - 1978
Externally publishedYes

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