Human amniotic fluids, obtained by amniocentesis at 16-24 weeks of gestation, were analyzed for epidermal growth factor (EGF) by using a heterologous radioimmunoassay. The range of EGF in 28 amniotic fluids was 0.06-1 ng/ml. Much higher levels of EGF up to 26 ng/ml, were detected in 3 amniotic fluids. Competitive binding assays and chromatography of concentrated amniotic fluids provided additional evidence for the presence of immunoreactive EGF in amniotic fluid.
|Number of pages||6|
|Journal||Mount Sinai Journal of Medicine|
|State||Published - 1978|