Immunomodulation by soluble factors from tumor cells cultured in vivo in diffusion chambers

Slobodanka Klein, Maria Adela Jasnis, Miriam Diament, Lilia Davel, Julio Aguirre, Yolanda P. de Bonaparte

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The delayed-type hypersensitivity (DTH) response and lym- phocyte-mediated angiogenesis were determined in mice bearing in vivo cultures of mammary tumor cells in diffusion chambers (DCs). Soluble tumor products which diffuse from the DCs were able to stimulate the immune system for both the DTH reaction and angiogenic activity by spleen cells.

Original languageEnglish
Pages (from-to)160-165
Number of pages6
JournalTumor Biology
Volume15
Issue number3
DOIs
StatePublished - 1994
Externally publishedYes

Keywords

  • Angiogenesis
  • Delayed-type hypersensitivity
  • Diffusion chambers
  • Tumor cells

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