Immunohistochemical and electron microscopic studies of Langerhans' cell histiocytosis (Eosinophilic granuloma) of the orbit

I. Rand Rodgers; Ramon L. Font; Alan H. Friedman; Samuel L. Guillory; Frederick A. Jakobiec; Milton Boniuk

Immunohistochemical and electron microscopic studies of Langerhans' cell histiocytosis (Eosinophilic granuloma) of the orbit

I. Rand Rodgers, Ramon L. Font, Alan H. Friedman, Samuel L. Guillory, Frederick A. Jakobiec, Milton Boniuk

Research output: Contribution to journal › Article › peer-review

Abstract

Immunophenotypic and histochemical studies have shown that Langerhans' cell histiocytosis results from an abnormal proliferation of dendritic cells. Characterized by a cytoplasm containing Birbeck granules and S-100 protein, these cells elaborate the surface glycoprotein T-6. We report here two cases of eosinophilic granuloma and review the immunologic role of Langerhans' cells with attention focused upon their unique morphologic traits.

Original language	English
Pages (from-to)	24-29
Number of pages	6
Journal	Ophthalmic Practice
Volume	21
Issue number	1
State	Published - Jan 2003

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title = "Immunohistochemical and electron microscopic studies of Langerhans' cell histiocytosis (Eosinophilic granuloma) of the orbit",

abstract = "Immunophenotypic and histochemical studies have shown that Langerhans' cell histiocytosis results from an abnormal proliferation of dendritic cells. Characterized by a cytoplasm containing Birbeck granules and S-100 protein, these cells elaborate the surface glycoprotein T-6. We report here two cases of eosinophilic granuloma and review the immunologic role of Langerhans' cells with attention focused upon their unique morphologic traits.",

author = "Rodgers, {I. Rand} and Font, {Ramon L.} and Friedman, {Alan H.} and Guillory, {Samuel L.} and Jakobiec, {Frederick A.} and Milton Boniuk",

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AU - Font, Ramon L.

AU - Friedman, Alan H.

AU - Guillory, Samuel L.

AU - Jakobiec, Frederick A.

AU - Boniuk, Milton

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AB - Immunophenotypic and histochemical studies have shown that Langerhans' cell histiocytosis results from an abnormal proliferation of dendritic cells. Characterized by a cytoplasm containing Birbeck granules and S-100 protein, these cells elaborate the surface glycoprotein T-6. We report here two cases of eosinophilic granuloma and review the immunologic role of Langerhans' cells with attention focused upon their unique morphologic traits.

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Immunohistochemical and electron microscopic studies of Langerhans' cell histiocytosis (Eosinophilic granuloma) of the orbit

Abstract

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