Immunoglobulin production by human-mouse somatic cell hybrids.

M. Smith, K. Hirschhorn

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Studies on immunoglobulin production in human-mouse somatic cell hybrids suggest: 1. The structural genes for heavy chain immunoglobulins are carried on chromsome 6, probably on the short arm or the proximal half of the long arm of the chromosome. 2. The structural gene for kappa light chain immunoglobulin may be carried on chromsome 11. 3. The occurrence of immunoglobulin molecules on the cell surface requires the presence of chromosome 2.

Original languageEnglish
Pages (from-to)281-285
Number of pages5
JournalTransactions of the Association of American Physicians
Volume90
StatePublished - 1977

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