TY - JOUR
T1 - Immune evasion by dormant disseminated cancer cells
T2 - A Fermi paradox?
AU - Adam-Artigues, Anna
AU - Valencia Salazar, Luis E.
AU - Aguirre-Ghiso, Julio A.
N1 - Publisher Copyright:
© 2023 Elsevier Inc.
PY - 2024/1/8
Y1 - 2024/1/8
N2 - Rare disseminated tumor cells (DTCs) can persist after treatment in patients for years, and the immune system does not eliminate them. Goddard et al. propose that immune evasion by rare dormant DTCs is due to an improbability of contact imposed by large distances separating effector T cells and DTCs.
AB - Rare disseminated tumor cells (DTCs) can persist after treatment in patients for years, and the immune system does not eliminate them. Goddard et al. propose that immune evasion by rare dormant DTCs is due to an improbability of contact imposed by large distances separating effector T cells and DTCs.
UR - http://www.scopus.com/inward/record.url?scp=85181805061&partnerID=8YFLogxK
U2 - 10.1016/j.ccell.2023.12.017
DO - 10.1016/j.ccell.2023.12.017
M3 - Comment/debate
AN - SCOPUS:85181805061
SN - 1535-6108
VL - 42
SP - 13
EP - 15
JO - Cancer Cell
JF - Cancer Cell
IS - 1
ER -