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Immune cell-derived C3a and C5a costimulate human T cell alloimmunity
P. Cravedi
, J. Leventhal
, P. Lakhani
,
S. C. Ward
, M. J. Donovan
, P. S. Heeger
Icahn School of Medicine at Mount Sinai
Marc and Jennifer Lipschultz Precision Immunology Institute
Medicine
Medicine - Nephrology
Mount Sinai Academy of Physician-Scientists
Pathology, Molecular and Cell-Based Medicine
Graduate School of Biomedical Sciences
Research output
:
Contribution to journal
›
Article
›
peer-review
107
Scopus citations
Overview
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Dive into the research topics of 'Immune cell-derived C3a and C5a costimulate human T cell alloimmunity'. Together they form a unique fingerprint.
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Keyphrases
Immune Cells
100%
T Cells
100%
Cell-derived
100%
Alloimmunization
100%
C3aR
66%
C5aR
66%
Dendritic Cells
50%
T Cell Proliferation
33%
Graft-versus-host Disease (GvHD)
33%
T Cell Immunity
16%
SiRNA Knockdown
16%
Phosphorylation
16%
CD4+ T
16%
Recombinant
16%
Antigen-presenting Cells
16%
T Cell Response
16%
Inhibitory Effect
16%
T-cell Mediated
16%
In Vitro Culture
16%
Alloreactive
16%
Prolonged Survival
16%
Decay Accelerating Factor
16%
C5a Receptor
16%
CD4 T Cells
16%
Tolerogenic Dendritic Cells
16%
Reduced Graft
16%
Complement Regulatory Proteins
16%
Protein Decay
16%
Complement Activation Products
16%
Receptor Blockade
16%
Cell Signaling Pathways
16%
Alloresponse
16%
T Cell Signaling
16%
Organ Transplant Rejection
16%
Scid
16%
C5aR Antagonist
16%
Xenogeneic Graft-versus-host Disease
16%
Cellular Expression
16%
Murine T Cells
16%
Cytotoxic T-lymphocyte-associated Protein 4 (CTLA-4)
16%
Costimulatory Signal
16%
Human Peripheral Blood Mononuclear Cells (hPBMCs)
16%
Disease Score
16%
Costimulatory
16%
Immunology and Microbiology
Immunocompetent Cell
100%
T Cell
100%
Complement Component 5a
100%
Alloimmunity
100%
Dendritic Cell
57%
Graft-Versus-Host Disease
42%
T-Helper Cell
28%
T Cell Proliferation
28%
Adoptive Immunity
14%
Antigen Presenting Cell
14%
Signal Transduction
14%
Antigen-Presenting Cell
14%
Complement Component C5a Receptor
14%
Transplant Rejection
14%
Decay-Accelerating Factor
14%
Cell Expansion
14%
Complement Activation
14%
Receptor Blocking
14%
T-Cell Signaling
14%
Abatacept
14%
Peripheral Blood Mononuclear Cell
14%
In Vitro
14%
phosphorylation
14%