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Immune cell-derived C3a and C5a costimulate human T cell alloimmunity
P. Cravedi
, J. Leventhal
, P. Lakhani
,
S. C. Ward
, M. J. Donovan
, P. S. Heeger
Icahn School of Medicine at Mount Sinai
Marc and Jennifer Lipschultz Precision Immunology Institute
Medicine
Medicine - Nephrology
Pathology, Molecular and Cell-Based Medicine
Graduate School of Biomedical Sciences
Research output
:
Contribution to journal
›
Article
›
peer-review
104
Scopus citations
Overview
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Dive into the research topics of 'Immune cell-derived C3a and C5a costimulate human T cell alloimmunity'. Together they form a unique fingerprint.
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Keyphrases
Immune Cells
100%
T Cells
100%
Cell-derived
100%
Alloimmunization
100%
C3aR
57%
C5aR
57%
Dendritic Cells
42%
T Cell Proliferation
28%
Costimulatory Molecules
28%
Graft-versus-host Disease (GvHD)
28%
Akt Phosphorylation
14%
T Cell Immunity
14%
SiRNA Knockdown
14%
CD4+ T
14%
Recombinant
14%
Antigen-presenting Cells
14%
T Cell Response
14%
Inhibitory Effect
14%
T-cell Mediated
14%
Cellular Expression
14%
In Vitro Culture
14%
Alloreactive
14%
Prolonged Survival
14%
Decay Accelerating Factor
14%
C5a Receptor
14%
CD4 T Cells
14%
Tolerogenic Dendritic Cells
14%
Disease Score
14%
Cytotoxic T-lymphocyte antigen-4 (CTLA-4)
14%
Reduced Graft
14%
Peripheral Blood Mononuclear Cells
14%
Complement Regulatory Proteins
14%
Protein Decay
14%
Cell Expansion
14%
Complement Activation Products
14%
Receptor Blockade
14%
Cell Signaling Pathways
14%
Alloresponse
14%
T Cell Signaling
14%
Organ Transplant Rejection
14%
Scid
14%
C5aR Antagonist
14%
Xenogeneic Graft-versus-host Disease
14%
Immunology and Microbiology
Immunocompetent Cell
100%
T Cell
100%
Complement Component 5a
100%
Alloimmunity
100%
Dendritic Cell
57%
Graft-Versus-Host Disease
42%
T-Helper Cell
28%
T Cell Proliferation
28%
Adoptive Immunity
14%
Antigen Presenting Cell
14%
Antigen-Presenting Cell
14%
Complement Component C5a Receptor
14%
Transplant Rejection
14%
Decay-Accelerating Factor
14%
Cell Expansion
14%
Complement Activation
14%
Receptor Blocking
14%
T-Cell Signaling
14%
Abatacept
14%
Peripheral Blood Mononuclear Cell
14%
In Vitro
14%