Image subtraction in gadolinium-enhanced MR imaging

Vivian S. Lee, Mark A. Flyer, Jeffrey C. Weinreb, Glenn A. Krinsky, Neil M. Rofsky

Research output: Contribution to journalReview articlepeer-review

54 Scopus citations


Image subtraction in gadolinium-enhanced MR imaging is a broadly applicable postprocessing technique that can be used with any field strength and TI-weighted sequence. This technique is typically a quick and efficient means of obtaining fat suppression that avoids the limitations of incomplete fat saturation due to field inhomogeneity and increased imaging times associated with conventional fat-suppression techniques. In particular, image subtraction may be valuable on lower strength magnetic field systems that lack effective chemical-shift fat-suppression techniques. Because source data are viewed in conjunction with subtracted images, image subtraction is unlikely to introduce errors in interpretation. By performing unenhanced and enhanced sequences in a manner amenable to image subtraction, radiologists should find this technique to be a useful and almost costfree option.

Original languageEnglish
Pages (from-to)1427-1432
Number of pages6
JournalAmerican Journal of Roentgenology
Issue number6
StatePublished - 1996
Externally publishedYes


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