IgA Summons IgG to Take a Hit at HIV-1

Giuliana Magri, Andrea Cerutti

Research output: Contribution to journalComment/debate

2 Scopus citations

Abstract

In this issue of Cell Host & Microbe, Jia et al. used a vesicular stomatitis virus-based probe to isolate B cells expressing broadly neutralizing HIV-1 antibodies. Besides identifying neutralizing epitopes, this study highlights potential protection afforded by IgA arising from either direct IgM-to-IgA or sequential IgM-to-IgG-to-IgA class switching.

Original languageEnglish
Pages (from-to)854-856
Number of pages3
JournalCell Host and Microbe
Volume27
Issue number6
DOIs
StatePublished - 10 Jun 2020

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