IgA-dominant glomerulonephritis associated with hepatitis A

S. R. Cheema, F. Arif, D. Charney, I. S. Meisels, S. S. Cheema

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14 Scopus citations


Unlike hepatitis B and C, renal involvement has been extremely uncommon in patients with hepatitis A virus (HAV) infection. Nephrotic syndrome has been documented as a rare complication in association with HAV infection. In this report, we describe a patient with serologically documented HAV infection, who presented with nephrotic syndrome. The renal biopsy showed an immunoglobulin A- (IgA) dominant glomerulonephritis (GN) with subendothelial immune deposits. This is the second biopsy-proven case report of a patient with acute HAV associated with IgA-dominant immune complex glornerulonephritis and nephrotic syndrome. This is perhaps the first case in which a patient experienced both IgA-dominant glomerulonephritis and cutaneous cryoglobulinemic vasculitis.

Original languageEnglish
Pages (from-to)138-143
Number of pages6
JournalClinical Nephrology
Issue number2
StatePublished - Aug 2004
Externally publishedYes


  • Cryoglobulin
  • Glomerulonephritis
  • Hepatitis A
  • Iga nephropathy
  • Nephrotic syndrome


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