IgA Antibody to Spermatozoa in Seminal and Prostatic Fluids of a Subfertile Man

Steven S. Witkin; Gerald Zelikovsky; Ann Marie Bongiovanni; Robert A. Good; Noorbibi K. Day

doi:10.1001/jama.1982.03320320050030

IgA Antibody to Spermatozoa in Seminal and Prostatic Fluids of a Subfertile Man

Steven S. Witkin, Gerald Zelikovsky, Ann Marie Bongiovanni, Robert A. Good, Noorbibi K. Day

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

The mechanism of spontaneous sperm agglutination in the ejaculate of a subfertile man was investigated. Using enzyme-linked immunosorbent assays it was found that the patient's spermatozoa had a mean of 2.3 times more IgA bound to it than did spermatozoa from fertile men. IgA antibody to spermatozoa was also found in the patient's seminal fluid and prostatic fluid, but not in his serum. In this patient it appeared that agglutination was due to an IgA antibody to spermatozoa that was produced locally within the genital tract.

Original language	English
Pages (from-to)	1014-1015
Number of pages	2
Journal	JAMA - Journal of the American Medical Association
Volume	247
Issue number	7
DOIs	https://doi.org/10.1001/jama.1982.03320320050030
State	Published - 19 Feb 1982
Externally published	Yes

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title = "IgA Antibody to Spermatozoa in Seminal and Prostatic Fluids of a Subfertile Man",

abstract = "The mechanism of spontaneous sperm agglutination in the ejaculate of a subfertile man was investigated. Using enzyme-linked immunosorbent assays it was found that the patient's spermatozoa had a mean of 2.3 times more IgA bound to it than did spermatozoa from fertile men. IgA antibody to spermatozoa was also found in the patient's seminal fluid and prostatic fluid, but not in his serum. In this patient it appeared that agglutination was due to an IgA antibody to spermatozoa that was produced locally within the genital tract.",

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AU - Witkin, Steven S.

AU - Zelikovsky, Gerald

AU - Bongiovanni, Ann Marie

AU - Good, Robert A.

AU - Day, Noorbibi K.

PY - 1982/2/19

Y1 - 1982/2/19

N2 - The mechanism of spontaneous sperm agglutination in the ejaculate of a subfertile man was investigated. Using enzyme-linked immunosorbent assays it was found that the patient's spermatozoa had a mean of 2.3 times more IgA bound to it than did spermatozoa from fertile men. IgA antibody to spermatozoa was also found in the patient's seminal fluid and prostatic fluid, but not in his serum. In this patient it appeared that agglutination was due to an IgA antibody to spermatozoa that was produced locally within the genital tract.

AB - The mechanism of spontaneous sperm agglutination in the ejaculate of a subfertile man was investigated. Using enzyme-linked immunosorbent assays it was found that the patient's spermatozoa had a mean of 2.3 times more IgA bound to it than did spermatozoa from fertile men. IgA antibody to spermatozoa was also found in the patient's seminal fluid and prostatic fluid, but not in his serum. In this patient it appeared that agglutination was due to an IgA antibody to spermatozoa that was produced locally within the genital tract.

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JF - JAMA - Journal of the American Medical Association

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ER -

IgA Antibody to Spermatozoa in Seminal and Prostatic Fluids of a Subfertile Man

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