Idiopathic granulomatous lobular mastitis

Frederick A. Pereira, Adarsh V. Mudgil, Edgar S. Macias, Karen Karsif

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations


Idiopathic granulomatous lobular mastitis (IGLM) is a rare breast condition with prominent skin findings. It is typically seen in young parous women. Painful breast masses, draining sinuses, scarring, and breast atrophy are the main clinical manifestations. IGLM can resemble a variety of other inflammatory and neoplastic processes of the breast. It is thought to result from obstruction and rupture of breast lobules. Extravasated breast secretions then induce an inflammatory reaction. Corynebacteria have also been implicated in the pathogenesis. Treatment is surgical, but systemic corticosteroids, methotrexate, and antibiotics also play a role.

Original languageEnglish
Pages (from-to)142-151
Number of pages10
JournalInternational Journal of Dermatology
Issue number2
StatePublished - Feb 2012


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