Idiopathic dilated cardiomyopathy

Catherine E. Cooke, Michael D. Greenberg, Steven S. Coughlin, Kenneth Mishark, Masato Odawara, Kamejiro Yamashita, Sewa S. Legha, G. W. Dec, Valentin Fuster

Research output: Contribution to journalLetterpeer-review

7 Scopus citations


To the Editor: Dec and Fuster (Dec. 8 issue)1 categorized the use of beta-blockers in patients with idiopathic dilated cardiomyopathy as investigational. There is now sufficient evidence to support their use as adjunctive therapy. Numerous clinical trials have evaluated the use of beta-blockers in conjunction with angiotensin-converting—enzyme inhibitors, nitrates, diuretics, and digoxin in patients with idiopathic dilated cardiomyopathy and have found improvements in ejection fraction, cardiac index, and New York Heart Association class and a decreased number of hospital admissions and cardiac transplantations.24 However, there have been trials5,6 that did not show such improvements. This is probably because.

Original languageEnglish
Pages (from-to)1384-1386
Number of pages3
JournalNew England Journal of Medicine
Issue number20
StatePublished - 18 May 1995
Externally publishedYes


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