Identification of the Whipple's Disease Bacillus

Kenneth H. Wilson; Rhonda B. Blitchington; Richard Frothingham; Joanne A.p. Wilson; Charles R. Steinman; Peter Rumore; David A. Relman; Richard P. Macdermott; Thomas M. Schmidt

doi:10.1056/NEJM199301073280113

Identification of the Whipple's Disease Bacillus

Kenneth H. Wilson
, Rhonda B. Blitchington
, Richard Frothingham
, Joanne A.p. Wilson
, Charles R. Steinman
, Peter Rumore
, David A. Relman
, Richard P. Macdermott
, Thomas M. Schmidt

Research output: Contribution to journal › Letter › peer-review

8 Scopus citations

Abstract

To the Editor: We were puzzled by the recent report by Relman et al. (July 30 issue)¹ confirming the identification of the Whipple's disease bacillus. A year ago in The Lancet we also reported that the Whipple bacillus was a gram-positive bacterium rich in guanine and cytosine (an actinomycete) not closely related to any other known organism². Our report showed that the biopsy specimen of small intestine from a patient with Whipple's disease contained massive numbers of a bacterial agent with the same 16S rRNA sequence as that confirmed and extended by Relman et al. We later reported using…

Original language	English
Pages (from-to)	62-63
Number of pages	2
Journal	New England Journal of Medicine
Volume	328
Issue number	1
DOIs	https://doi.org/10.1056/NEJM199301073280113
State	Published - 7 Jan 1993
Externally published	Yes

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title = "Identification of the Whipple's Disease Bacillus",

abstract = "To the Editor: We were puzzled by the recent report by Relman et al. (July 30 issue)1 confirming the identification of the Whipple's disease bacillus. A year ago in The Lancet we also reported that the Whipple bacillus was a gram-positive bacterium rich in guanine and cytosine (an actinomycete) not closely related to any other known organism2. Our report showed that the biopsy specimen of small intestine from a patient with Whipple's disease contained massive numbers of a bacterial agent with the same 16S rRNA sequence as that confirmed and extended by Relman et al. We later reported using…",

author = "Wilson, \{Kenneth H.\} and Blitchington, \{Rhonda B.\} and Richard Frothingham and Wilson, \{Joanne A.p.\} and Steinman, \{Charles R.\} and Peter Rumore and Relman, \{David A.\} and Macdermott, \{Richard P.\} and Schmidt, \{Thomas M.\}",

year = "1993",

month = jan,

day = "7",

doi = "10.1056/NEJM199301073280113",

language = "English",

volume = "328",

pages = "62--63",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachussetts Medical Society",

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TY - JOUR

T1 - Identification of the Whipple's Disease Bacillus

AU - Wilson, Kenneth H.

AU - Blitchington, Rhonda B.

AU - Frothingham, Richard

AU - Wilson, Joanne A.p.

AU - Steinman, Charles R.

AU - Rumore, Peter

AU - Relman, David A.

AU - Macdermott, Richard P.

AU - Schmidt, Thomas M.

PY - 1993/1/7

Y1 - 1993/1/7

N2 - To the Editor: We were puzzled by the recent report by Relman et al. (July 30 issue)1 confirming the identification of the Whipple's disease bacillus. A year ago in The Lancet we also reported that the Whipple bacillus was a gram-positive bacterium rich in guanine and cytosine (an actinomycete) not closely related to any other known organism2. Our report showed that the biopsy specimen of small intestine from a patient with Whipple's disease contained massive numbers of a bacterial agent with the same 16S rRNA sequence as that confirmed and extended by Relman et al. We later reported using…

AB - To the Editor: We were puzzled by the recent report by Relman et al. (July 30 issue)1 confirming the identification of the Whipple's disease bacillus. A year ago in The Lancet we also reported that the Whipple bacillus was a gram-positive bacterium rich in guanine and cytosine (an actinomycete) not closely related to any other known organism2. Our report showed that the biopsy specimen of small intestine from a patient with Whipple's disease contained massive numbers of a bacterial agent with the same 16S rRNA sequence as that confirmed and extended by Relman et al. We later reported using…

UR - https://www.scopus.com/pages/publications/0027472185

U2 - 10.1056/NEJM199301073280113

DO - 10.1056/NEJM199301073280113

M3 - Letter

C2 - 7677948

AN - SCOPUS:0027472185

SN - 0028-4793

VL - 328

SP - 62

EP - 63

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 1

ER -

Identification of the Whipple's Disease Bacillus

Abstract

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