Identical twins concordant for Crohn's disease

  • Scott M. Sirlin
  • , Keith J. Benkov
  • , Phillip Kazlow
  • , Stephen Dolgin
  • , M. Renate Dische
  • , Neal S. LeLeiko

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Identical twin adolescent girls developed Crohn's disease within 15 months of each other. Clinical symptoms, growth retardation, barium studies, disease course, and pathologic findings at the time of resection were remarkably similar. Seventeen pairs of twins concordant for Crohn's disease have now been reported, but only four discordant pairs. Such observations lend support to a considerable genetic influence on the development and course of Crohn's disease.

Original languageEnglish
Pages (from-to)290-294
Number of pages5
JournalJournal of Clinical Gastroenterology
Volume8
Issue number3
DOIs
StatePublished - Jun 1986

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