Ibuprofen for pain relief after surgical removal of lower wisdom teeth

This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the beneficial and harmful effects of ibuprofen for pain relief after surgical removal of lower wisdom teeth, compared to placebo, at different doses and administered preoperatively or postoperatively. Primary: To test the null hypothesis of no difference in the beneficial and harmful effects between ibuprofen and placebo for pain relief in patients requiring surgical removal of a lower wisdom tooth or teeth, against the alternative hypothesis of a difference. Secondary: To test the null hypothesis of no difference in the beneficial and harmful effects between different doses of ibuprofen for pain relief in patients requiring surgical removal of a lower wisdom tooth or teeth, against the alternative hypothesis of a difference. To test the null hypothesis of no difference in the beneficial and harmful effects between different times of administration of ibuprofen for pain relief in patients requiring surgical removal of a lower wisdom tooth or teeth, against the alternative hypothesis of a difference.