Hypothyroidism due to Hashimoto's thyroiditis masked by anorexia nervosa

Adjoa Smalls-Mantey; Joanna Steinglass; Marshall Primack; Jill Clark-Hamilton; Mary Bongiovi

doi:10.1002/eat.22420

Hypothyroidism due to Hashimoto's thyroiditis masked by anorexia nervosa

Adjoa Smalls-Mantey, Joanna Steinglass, Marshall Primack, Jill Clark-Hamilton, Mary Bongiovi

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7 Scopus citations

Abstract

Anorexia nervosa (AN) is typically associated with altered thyroid function tests, notably a low total and free T₃, and lower, but within normal range, free T₄ and TSH. A 16-year-old girl with a four-year history of AN presented with elevated TSH that fluctuated with changes in weight. TSH was within normal limits (1.7-3.64 mIU/L) following periods of weight loss and elevated with weight gain (5.9-21.66 mIU/L). Antithyroperoxidase antibodies were markedly elevated, suggesting chronic Hashimoto's thyroiditis. Of note, the elevated TSH that would be expected in Hashimoto's thyroiditis was blunted by weight loss associated with AN. Physicians should be aware that AN may contribute to masking thyroid abnormalities in Hashimoto's thyroiditis.

Original language	English
Pages (from-to)	932-935
Number of pages	4
Journal	International Journal of Eating Disorders
Volume	48
Issue number	7
DOIs	https://doi.org/10.1002/eat.22420
State	Published - Nov 2015
Externally published	Yes

Keywords

Hashimoto's thyroiditis
TSH
anorexia nervosa
hypothyroidism

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title = "Hypothyroidism due to Hashimoto's thyroiditis masked by anorexia nervosa",

abstract = "Anorexia nervosa (AN) is typically associated with altered thyroid function tests, notably a low total and free T3, and lower, but within normal range, free T4 and TSH. A 16-year-old girl with a four-year history of AN presented with elevated TSH that fluctuated with changes in weight. TSH was within normal limits (1.7-3.64 mIU/L) following periods of weight loss and elevated with weight gain (5.9-21.66 mIU/L). Antithyroperoxidase antibodies were markedly elevated, suggesting chronic Hashimoto's thyroiditis. Of note, the elevated TSH that would be expected in Hashimoto's thyroiditis was blunted by weight loss associated with AN. Physicians should be aware that AN may contribute to masking thyroid abnormalities in Hashimoto's thyroiditis.",

keywords = "Hashimoto's thyroiditis, TSH, anorexia nervosa, hypothyroidism",

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AU - Steinglass, Joanna

AU - Primack, Marshall

AU - Clark-Hamilton, Jill

AU - Bongiovi, Mary

PY - 2015/11

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AB - Anorexia nervosa (AN) is typically associated with altered thyroid function tests, notably a low total and free T3, and lower, but within normal range, free T4 and TSH. A 16-year-old girl with a four-year history of AN presented with elevated TSH that fluctuated with changes in weight. TSH was within normal limits (1.7-3.64 mIU/L) following periods of weight loss and elevated with weight gain (5.9-21.66 mIU/L). Antithyroperoxidase antibodies were markedly elevated, suggesting chronic Hashimoto's thyroiditis. Of note, the elevated TSH that would be expected in Hashimoto's thyroiditis was blunted by weight loss associated with AN. Physicians should be aware that AN may contribute to masking thyroid abnormalities in Hashimoto's thyroiditis.

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Hypothyroidism due to Hashimoto's thyroiditis masked by anorexia nervosa

Abstract

Keywords

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