Hypopharyngeal cancer: A state of the art review

Jonathan C. Garneau, Richard L. Bakst, Brett A. Miles

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


Cancer of the hypopharynx is relatively rare and accounts for roughly 3% of all head and neck cancers. Unfortunately, hypopharyngeal carcinoma has one of the worst prognosis of all head and neck cancers with a reported 5-year overall survival rate of approximately 30–35%. Toxicity related to therapy, and the need for surgical salvage continue to dominate the landscape in this disease. In this article, we set out to discuss a comprehensive overview of the current management principles, recent literature and evidence based therapeutic options surrounding treatment for hypopharyngeal squamous cell carcinoma, with a special focus on the evolution of an organ sparing paradigm.

Original languageEnglish
Pages (from-to)244-250
Number of pages7
JournalOral Oncology
StatePublished - Nov 2018


  • Head and neck squamous cell carcinoma
  • Hypopharyngeal cancer
  • Hypopharyngeal carcinoma
  • Laryngeal preservation


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