Hyperplasie nodulaire lymphoide pseudo-tumorale de l'ileon

Translated title of the contribution: Pseudotumoral ileal nodular lymphoid hyperplasia

Laure Vayre-Oundjian, Arnaud Boruchowicz, Florence Bloget, Jean Pierre Triboulet, Bernard Gosselin, Jean Frédéric Colombel

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


We report a case of pseudotumoral nodular lymphoid hyperplasia of the ileum in an immunocompetent 62-year-old woman. Ileoscopy showed multiple voluminous, soft, pliable, polypoid ileal lesions. Perendoscopic biopsies revealed a florid inflammation of the mucosa, characterized by numerous enlarged follicles with well-developed reactive germinal centres separated by a mixed infiltrate of lymphocytes, plasma cells and eosinophils. Immunohistochemistry showed a polytypic staining for kappa and lambda light- chains in the follicles and between and confirmed the reactive nature of the infiltrate. CT scan of the abdomen disclosed large periileal lymph nodes and a right ileocolectomy was performed. Twelve cases of pseudotumoral nodular lymphoid hyperplasia of the ileum have been reported in the literature in patients older than 25. In all cases, the diagnosis was performed after laparotomy. As shown in our case report, the diagnosis is possible on multiple perendoscopic biopsies.

Translated title of the contributionPseudotumoral ileal nodular lymphoid hyperplasia
Original languageFrench
Pages (from-to)990-993
Number of pages4
JournalGastroenterologie Clinique et Biologique
Issue number12
StatePublished - Dec 1997
Externally publishedYes


  • Ileum
  • MALT lymphoma
  • Multiple lymphomatous polyposis (mantle cell lymphoma)
  • Polypoid nodular lymphoid hyperplasia


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