Hypernatremia without water depletion

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Hypernatremia is generally thought to be a condition in which water depletion raises the serum sodium concentration despite some salt loss. However, many patients with hypernatremia have been shown to have normal or increased total body water, indicating that these patients are salt- and frequently water-overloaded. Possible pathophysiological reasons for these abnormalities are discussed. Recognition of this clinical condition is important because therapy should avoid further worsening the salt and water overload.

Original languageEnglish
Pages (from-to)130-135
Number of pages6
JournalClinical Nephrology
Issue number2
StatePublished - Aug 2011
Externally publishedYes


  • Antidiuretic hormone
  • Hypernatremia
  • Osmolality
  • Salt
  • Sodium
  • Volume


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