Replication-competent retroviruses are not known to encode or induce nuclear antigens that are immunogenic in their natural hosts. We describe here the detection of a human T-lymphotropic virus (type I and type II) associated nuclear antigen (HTLV-NA) by an anticomplement immunofluorescence assay. Antibody to HTLV-NA is detected in 18 of 68 (26%) HTLV-I seropositives.
- (type I)
- (type II)
- Anti-complement immunofluorescence assay
- associated nuclear antigen
- human T-lymphotropic virus