Human fibroblasts produce "pregnancy-specific" beta-1 glycoprotein in vitro

Saul W. Rosen; Janina Kaminska; Ida S. Calvert; Stuart A. Aaronson

doi:10.1016/0002-9378(79)90938-4

Human fibroblasts produce "pregnancy-specific" beta-1 glycoprotein in vitro

Saul W. Rosen, Janina Kaminska, Ida S. Calvert, Stuart A. Aaronson

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Normal and genetic variant strains of nonrnalignant human fibroblasts produce in vitro a substance indistinguishable from the recently described "pregnancy-specific" beta-1 gtycoprotein (PSβG, PAPP-C, SP₁). Demonstration of this presumed placenta-specific meterial in a nonplacental site raises questions about its :normal physiologic role and use as a cancer marker.

Original language	English
Pages (from-to)	734-738
Number of pages	5
Journal	American Journal of Obstetrics and Gynecology
Volume	134
Issue number	7
DOIs	https://doi.org/10.1016/0002-9378(79)90938-4
State	Published - 1 Aug 1979
Externally published	Yes

Access to Document

10.1016/0002-9378(79)90938-4

Cite this

@article{85018f77def747428b922b784b9adf21,

title = "Human fibroblasts produce {"}pregnancy-specific{"} beta-1 glycoprotein in vitro",

abstract = "Normal and genetic variant strains of nonrnalignant human fibroblasts produce in vitro a substance indistinguishable from the recently described {"}pregnancy-specific{"} beta-1 gtycoprotein (PSβG, PAPP-C, SP1). Demonstration of this presumed placenta-specific meterial in a nonplacental site raises questions about its :normal physiologic role and use as a cancer marker.",

author = "Rosen, {Saul W.} and Janina Kaminska and Calvert, {Ida S.} and Aaronson, {Stuart A.}",

year = "1979",

month = aug,

day = "1",

doi = "10.1016/0002-9378(79)90938-4",

language = "English",

volume = "134",

pages = "734--738",

journal = "American Journal of Obstetrics and Gynecology",

issn = "0002-9378",

publisher = "Elsevier Inc.",

number = "7",

}

TY - JOUR

T1 - Human fibroblasts produce "pregnancy-specific" beta-1 glycoprotein in vitro

AU - Rosen, Saul W.

AU - Kaminska, Janina

AU - Calvert, Ida S.

AU - Aaronson, Stuart A.

PY - 1979/8/1

Y1 - 1979/8/1

N2 - Normal and genetic variant strains of nonrnalignant human fibroblasts produce in vitro a substance indistinguishable from the recently described "pregnancy-specific" beta-1 gtycoprotein (PSβG, PAPP-C, SP1). Demonstration of this presumed placenta-specific meterial in a nonplacental site raises questions about its :normal physiologic role and use as a cancer marker.

AB - Normal and genetic variant strains of nonrnalignant human fibroblasts produce in vitro a substance indistinguishable from the recently described "pregnancy-specific" beta-1 gtycoprotein (PSβG, PAPP-C, SP1). Demonstration of this presumed placenta-specific meterial in a nonplacental site raises questions about its :normal physiologic role and use as a cancer marker.

UR - http://www.scopus.com/inward/record.url?scp=0018423665&partnerID=8YFLogxK

U2 - 10.1016/0002-9378(79)90938-4

DO - 10.1016/0002-9378(79)90938-4

M3 - Article

C2 - 88900

AN - SCOPUS:0018423665

SN - 0002-9378

VL - 134

SP - 734

EP - 738

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

IS - 7

ER -

Human fibroblasts produce "pregnancy-specific" beta-1 glycoprotein in vitro

Abstract

Access to Document

Fingerprint

Cite this