HPV Associated Squamous Cell Carcinoma in the Rectal Tonsil

Ketav Desai, Brett Baskovich, Ahmad Alkhasawneh, Khaled Mohamed, Reeba Omman, Arun Gopinath

Research output: Contribution to journalArticlepeer-review


Mucosa-associated lymphoid tissue has been reported throughout the gastrointestinal tract including rectum. Rarely, a nodular proliferation of predominantly submucosal lymphoid tissue in the rectum has been documented as rectal tonsil. Here we report a patient with HPV-associated squamous cell carcinoma of the rectal tonsil, presenting as a polyp. Previously, rare reports of HPV-associated lymphoepithelial carcinoma have been reported in the literature. We are presenting an extremely rare occurrence and emphasizing the importance of appropriate nomenclature based on the pathogenesis of the neoplasm.

Original languageEnglish
Pages (from-to)312-315
Number of pages4
JournalInternational Journal of Surgical Pathology
Issue number3
StatePublished - May 2023
Externally publishedYes


  • HPV
  • carcinoma
  • rectal
  • squamous
  • tonsil


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