There is a major gap in our understanding of how childhood social isolation causes adult social dysfunction. To stimulate future developmental mechanistic studies, we present two conceptual models which highlight that isolation can disrupt developmental events that are concurrent (social deprivation model) or subsequent (developmental mismatch model) to adverse experience.

Original languageEnglish
JournalTrends in Cognitive Sciences
StateAccepted/In press - 2024


  • brain maturation
  • developmental mismatch
  • social behavior
  • social experience
  • social isolation


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