How cells know they are in G1 or G2

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24 Scopus citations


How does a cell know if it's in G1 or G2 and should proceed to S phase or mitosis? This is a restatement of the question of how a cell ensures mitosis is dependent upon S phase, and S phase is dependent upon mitosis. Several gene products have been identified which play important roles in maintaining these interdependencies. Central to these controls are oscillations between different complexes of cyclins and cyclin-dependent kinases.

Original languageEnglish
Pages (from-to)867-871
Number of pages5
JournalCurrent Opinion in Cell Biology
Issue number6
StatePublished - Dec 1994
Externally publishedYes


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