Host modification on the skin allograft assay

M. Margaret Kemeny; Paul H. Sugarbaker

doi:10.1016/0022-4804(82)90137-8

Host modification on the skin allograft assay

M. Margaret Kemeny, Paul H. Sugarbaker

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Proliferating T cells are necessary for an accelerated rejection of a skin allograft. Irradiation of the host will not alter the ability of sensitized cells to cause this accelerated rejection. Neither does host splenectomy have an effect on these cytotoxic cells. Only host treatment with carrageenan, a macrophage inhibitor, can abrogate the effect of these specifically sensitized cells.

Original language	English
Pages (from-to)	540-546
Number of pages	7
Journal	Journal of Surgical Research
Volume	32
Issue number	6
DOIs	https://doi.org/10.1016/0022-4804(82)90137-8
State	Published - Jun 1982
Externally published	Yes

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title = "Host modification on the skin allograft assay",

abstract = "Proliferating T cells are necessary for an accelerated rejection of a skin allograft. Irradiation of the host will not alter the ability of sensitized cells to cause this accelerated rejection. Neither does host splenectomy have an effect on these cytotoxic cells. Only host treatment with carrageenan, a macrophage inhibitor, can abrogate the effect of these specifically sensitized cells.",

author = "{Margaret Kemeny}, M. and Sugarbaker, {Paul H.}",

year = "1982",

month = jun,

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AU - Margaret Kemeny, M.

AU - Sugarbaker, Paul H.

PY - 1982/6

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N2 - Proliferating T cells are necessary for an accelerated rejection of a skin allograft. Irradiation of the host will not alter the ability of sensitized cells to cause this accelerated rejection. Neither does host splenectomy have an effect on these cytotoxic cells. Only host treatment with carrageenan, a macrophage inhibitor, can abrogate the effect of these specifically sensitized cells.

AB - Proliferating T cells are necessary for an accelerated rejection of a skin allograft. Irradiation of the host will not alter the ability of sensitized cells to cause this accelerated rejection. Neither does host splenectomy have an effect on these cytotoxic cells. Only host treatment with carrageenan, a macrophage inhibitor, can abrogate the effect of these specifically sensitized cells.

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U2 - 10.1016/0022-4804(82)90137-8

DO - 10.1016/0022-4804(82)90137-8

M3 - Article

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SN - 0022-4804

VL - 32

SP - 540

EP - 546

JO - Journal of Surgical Research

JF - Journal of Surgical Research

IS - 6

ER -

Host modification on the skin allograft assay

Abstract

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