Hodgkin's lymphoma in an adolescent with systemic lupus erythematosus

Anna Efremidis, Arnold R. Eiser, Edith Grishman, Vladmiro Rosenberg

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

An adolescent female with systemic lupus erythematosus (SLE) with diffuse proliferative lupus nephritis subsequently contracted Hodgkin's lymphoma, mixed ceilularity type. Prior to the diagnosis of Hodgkin's lymphoma, hypogammaglobulinemia developed with IgG deficiency. The nephritis, which improved on steroid therapy, remitted entirely after nitrogen mustard, vincristine, procarbazine, and prednisone (MOPP) therapy. The hypogammaglobulinemia also remitted after chemotherapy for Hodgkin's lymphoma. The literature concerning the association of SLE and Hodgkin's lymphoma is reviewed. The significance of this concurrence is discussed in regard to the possible pathophysiology and the clinical management. Cancer 53:142‐146, 1984.

Original languageEnglish
Pages (from-to)142-146
Number of pages5
JournalCancer
Volume53
Issue number1
DOIs
StatePublished - 1 Jan 1984
Externally publishedYes

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