HLA-DQA1*05 Not Associated With Ustekinumab Loss of Response and Antidrug Antibodies in Ulcerative Colitis and Crohn’s Disease Patients

Jean Frédéric Colombel; María D. Martín-Arranz; Brigitta Brinkman; Meijian Guan; Amy Hart; Christopher Gasink

doi:10.1093/ibd/izad273

HLA-DQA1*05 Not Associated With Ustekinumab Loss of Response and Antidrug Antibodies in Ulcerative Colitis and Crohn’s Disease Patients

Jean Frédéric Colombel, María D. Martín-Arranz, Brigitta Brinkman, Meijian Guan, Amy Hart, Christopher Gasink

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

It is unknown if inflammatory bowel disease patients carrying the HLA-DQA1*05 allele have a greater risk of immunogenicity to ustekinumab.

Original language	English
Pages (from-to)	2227-2231
Number of pages	5
Journal	Inflammatory Bowel Diseases
Volume	30
Issue number	11
DOIs	https://doi.org/10.1093/ibd/izad273
State	Published - 1 Nov 2024

Keywords

antidrug antibodies
loss of response
ustekinumab

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10.1093/ibd/izad273

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title = "HLA-DQA1*05 Not Associated With Ustekinumab Loss of Response and Antidrug Antibodies in Ulcerative Colitis and Crohn{\textquoteright}s Disease Patients",

abstract = "It is unknown if inflammatory bowel disease patients carrying the HLA-DQA1*05 allele have a greater risk of immunogenicity to ustekinumab.",

keywords = "antidrug antibodies, loss of response, ustekinumab",

author = "Colombel, {Jean Fr{\'e}d{\'e}ric} and Mart{\'i}n-Arranz, {Mar{\'i}a D.} and Brigitta Brinkman and Meijian Guan and Amy Hart and Christopher Gasink",

year = "2024",

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doi = "10.1093/ibd/izad273",

language = "English",

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journal = "Inflammatory Bowel Diseases",

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T1 - HLA-DQA1*05 Not Associated With Ustekinumab Loss of Response and Antidrug Antibodies in Ulcerative Colitis and Crohn’s Disease Patients

AU - Colombel, Jean Frédéric

AU - Martín-Arranz, María D.

AU - Brinkman, Brigitta

AU - Guan, Meijian

AU - Hart, Amy

AU - Gasink, Christopher

PY - 2024/11/1

Y1 - 2024/11/1

N2 - It is unknown if inflammatory bowel disease patients carrying the HLA-DQA1*05 allele have a greater risk of immunogenicity to ustekinumab.

AB - It is unknown if inflammatory bowel disease patients carrying the HLA-DQA1*05 allele have a greater risk of immunogenicity to ustekinumab.

KW - antidrug antibodies

KW - loss of response

KW - ustekinumab

UR - http://www.scopus.com/inward/record.url?scp=85208514316&partnerID=8YFLogxK

U2 - 10.1093/ibd/izad273

DO - 10.1093/ibd/izad273

M3 - Article

C2 - 38029420

AN - SCOPUS:85208514316

SN - 1078-0998

VL - 30

SP - 2227

EP - 2231

JO - Inflammatory Bowel Diseases

JF - Inflammatory Bowel Diseases

IS - 11

ER -

HLA-DQA1*05 Not Associated With Ustekinumab Loss of Response and Antidrug Antibodies in Ulcerative Colitis and Crohn’s Disease Patients

Abstract

Keywords

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