HIV Drug to Aid Melanoma Therapies?

Hyungsoo Kim; Ze'ev A. Ronai

doi:10.1016/j.ccell.2016.02.014

HIV Drug to Aid Melanoma Therapies?

Hyungsoo Kim, Ze'ev A. Ronai

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

The HIV1 protease inhibitor nelfinavir is being investigated as a cancer therapeutic. In this issue of Cancer Cell, Smith et al. (2016) report that nelfinavir suppresses MITF expression induced by MAPK pathway inhibition in melanoma cells and sensitizes melanoma cells with NRAS or BRAF plus NRAS mutations to MEK inhibitors.

Original language	English
Pages (from-to)	245-246
Number of pages	2
Journal	Cancer Cell
Volume	29
Issue number	3
DOIs	https://doi.org/10.1016/j.ccell.2016.02.014
State	Published - 14 Mar 2016
Externally published	Yes

Access to Document

10.1016/j.ccell.2016.02.014

Cite this

@article{4ee4e3f718bc4525b5a9cf2c0d689191,

title = "HIV Drug to Aid Melanoma Therapies?",

abstract = "The HIV1 protease inhibitor nelfinavir is being investigated as a cancer therapeutic. In this issue of Cancer Cell, Smith et al. (2016) report that nelfinavir suppresses MITF expression induced by MAPK pathway inhibition in melanoma cells and sensitizes melanoma cells with NRAS or BRAF plus NRAS mutations to MEK inhibitors.",

author = "Hyungsoo Kim and Ronai, {Ze'ev A.}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = mar,

day = "14",

doi = "10.1016/j.ccell.2016.02.014",

language = "English",

volume = "29",

pages = "245--246",

journal = "Cancer Cell",

issn = "1535-6108",