TY - JOUR
T1 - HIV-associated neuropathic pain
T2 - Epidemiology, pathophysiology and management
AU - Verma, Susama
AU - Estanislao, Lydia
AU - Simpson, David
N1 - Funding Information:
This work was supported in part by National Institution of Health grants K24NS02253 (DS) and M01-RR-00071 (GCRC). Dr David Simpson has received grant support from Savient and is a consultant for Pfizer. Drs Lydia Estanislao and Susama Verma have no conflicts of interest relevant to the content of this article.
PY - 2005
Y1 - 2005
N2 - Peripheral neuropathy is associated with numerous systemic illnesses including HIV infection. Neuropathic pain constitutes approximately 25-50% of all pain clinic visits. Distal symmetrical polyneuropathy (DSP) is the most common form of peripheral neuropathy in individuals with HIV infection. DSP is distinguished from other forms of neuropathy on the basis of history and neurological examination. The pain associated with DSP can be debilitating. Therefore, it is important to diagnose HIV-associated DSP properly and treat the neuropathic pain in order to improve quality of life. We review the clinical manifestations, epidemiology, pathophysiology and management strategies for HIV-associated DSP.
AB - Peripheral neuropathy is associated with numerous systemic illnesses including HIV infection. Neuropathic pain constitutes approximately 25-50% of all pain clinic visits. Distal symmetrical polyneuropathy (DSP) is the most common form of peripheral neuropathy in individuals with HIV infection. DSP is distinguished from other forms of neuropathy on the basis of history and neurological examination. The pain associated with DSP can be debilitating. Therefore, it is important to diagnose HIV-associated DSP properly and treat the neuropathic pain in order to improve quality of life. We review the clinical manifestations, epidemiology, pathophysiology and management strategies for HIV-associated DSP.
UR - https://www.scopus.com/pages/publications/17844368598
U2 - 10.2165/00023210-200519040-00005
DO - 10.2165/00023210-200519040-00005
M3 - Review article
C2 - 15813646
AN - SCOPUS:17844368598
SN - 1172-7047
VL - 19
SP - 325
EP - 334
JO - CNS Drugs
JF - CNS Drugs
IS - 4
ER -